DCA dosing in published research varies depending on the condition studied, the population, and the study design. This article summarises what the peer-reviewed literature actually uses — not anecdotal reports.

The most commonly cited clinical dosing range for sodium DCA is 10–25 mg/kg/day, divided into two daily doses. For a 70kg adult, this translates to 700–1,750 mg per day. Most published human studies and observational reports cluster around the lower end of this range — 10–15 mg/kg/day — particularly for longer-duration protocols.

Cycle protocols matter. Peripheral neuropathy — the primary reported side effect of extended DCA use — is both dose-dependent and duration-dependent. The most commonly referenced cycle protocol in the literature is 2 weeks on followed by 1 week off, repeated as needed. Some researchers use shorter cycles of 5 days on, 2 days off.

B1 (thiamine) supplementation is frequently mentioned alongside DCA protocols in the research literature, as DCA may reduce thiamine-dependent enzyme activity over time. Alpha lipoic acid is sometimes also referenced as a protective adjunct.

DCA is a research compound. These dosing figures come from published studies — they are not medical advice. Anyone considering personal use of DCA should consult a qualified healthcare professional.

This article is for informational and educational purposes only. AuraDCA products are intended for research use only.